Targeted Delivery for Musculoskeletal Diseases

Targeted delivery of nanoparticles for the treatment of lung diseases.

Targeted delivery of drug molecules to organs or special sites is one of the most challenging research areas in pharmaceutical sciences. By developing colloidal delivery systems such as liposomes, micelles and nanoparticles a new frontier was opened for improving drug delivery. Nanoparticles with their special characteristics such as small particle size, large surface area and the capability of...

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

Musculoskeletal diseases--tendon.

INTRODUCTION Tendons establish specific connections between muscles and the skeleton by transferring contraction forces from skeletal muscle to bone thereby allowing body movement. Tendon physiology and pathology are heavily dependent on mechanical stimuli. Tendon injuries clinically represent a serious and still unresolved problem since damaged tendon tissues heal very slowly and no surgical t...

Musculoskeletal diseases in adolescence.

JIA has a prevalence of approximately 130 per 100,000 children. The classification has recently been changed (Table 1). Although principally a disease of younger children, JIA presents between the ages of 10 and 16 years in 25% of patients. Those who develop systemic or polyarticular disease at a younger age have a higher incidence of destructive joint disease. The common belief is that JIA ‘bu...